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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHM All Species: 29.39
Human Site: S238 Identified Species: 64.67
UniProt: P24386 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P24386 NP_000381.1 653 73476 S238 L V S K L L Y S R G L L I D L
Chimpanzee Pan troglodytes XP_521157 652 73433 S238 L V S K L L Y S R G L L I D L
Rhesus Macaque Macaca mulatta XP_001083432 653 73511 S238 L V S K L L Y S R G L L I D L
Dog Lupus familis XP_538092 652 73159 S237 L V S K L L Y S R G L L I D L
Cat Felis silvestris
Mouse Mus musculus Q9QXG2 665 73958 S250 L V S K L L Y S R G L L I D L
Rat Rattus norvegicus P37727 650 72462 S235 L V S Q L L Y S R G L L I D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026290 656 73072 S234 L V S K L L Y S R G L L I E L
Frog Xenopus laevis NP_001083662 643 71685 L232 F L Y S R G L L I E L L I K S
Zebra Danio Brachydanio rerio NP_982286 666 74108 D231 Y S R G A L V D L L I K S N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V8W3 511 56809 I122 G E L V Q L L I K S N I C R Y
Honey Bee Apis mellifera XP_001121784 523 59101 S134 K L T Q V P C S R A D V F A N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 97 88.2 N.A. 79.8 83.4 N.A. N.A. 65.8 56.5 55.5 N.A. 31.7 34.6 N.A. N.A.
Protein Similarity: 100 97.5 98.9 92.3 N.A. 86 89.2 N.A. N.A. 78.6 75.6 71.4 N.A. 48.7 53.5 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 93.3 20 6.6 N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 100 26.6 26.6 N.A. 20 46.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 10 0 0 55 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 10 0 0 0 10 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 10 0 0 10 0 10 0 0 0 64 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 10 0 10 10 73 0 0 % I
% Lys: 10 0 0 55 0 0 0 0 10 0 0 10 0 10 0 % K
% Leu: 64 19 10 0 64 82 19 10 10 10 73 73 0 0 64 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 10 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 19 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 10 0 0 0 73 0 0 0 0 10 0 % R
% Ser: 0 10 64 10 0 0 0 73 0 10 0 0 10 0 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 64 0 10 10 0 10 0 0 0 0 10 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 10 0 0 0 64 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _